Neutral Red

Chemical Structure : Neutral Red

CAS No.: 553-24-2

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货号: PC-20480Not For Human Use, Lab Use Only.

Neutral Red is a nitrogenous pH-indicator that can stains lysosomes red, also is a selective, uncompetitive USP4 inhibitor with IC50 of 50 uM.

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100 mg	￥1880	In stock
500 mg	￥2980	In stock
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生物&药学活性

Neutral Red is a nitrogenous pH-indicator that can stains lysosomes red, also is a selective, uncompetitive USP4 inhibitor with IC50 of 50 uM.
Neutral Red displays no effective activity on other DUBs (YOD1, USP5, UCHL1, and USP14).
Neutral Red inhibited the deubiquitinating activity of USP4 in colon cancer cells.
Neutral Red affected the protein stability of β-catenin, and the target genes expression of β-catenin.
Neutral Red significantly reduced colony formation and cell migration, reduced the tumor volume in mouse xenograft models.

物理化学性质&存储条件

分子量	288.78
分子式	C15H16N4.ClH
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2,8-Phenazinediamine, N8,N8,3-trimethyl-, monohydrochloride

参考文献

1. Nguyen HH, et al. Cell Physiol Biochem. 2019;53(1):157-171.

Neutral Red

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Neutral Red

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