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首页-小分子抑制剂&激动剂-GPCR-Adenosine Receptor-Neladenoson dalanate hydrochloride
Neladenoson dalanate hydrochloride

Chemical Structure : Neladenoson dalanate hydrochloride

CAS No.: 1239235-25-6

Neladenoson dalanate hydrochloride (BAY 10-67197)

货号: PC-63435Not For Human Use, Lab Use Only.

Neladenoson dalanate (BAY 10-67197) is a potent, selective, orally acitve partial adenosine A1 receptor (A1AR) agonist (EC50=0.1 nM) for the treatment of chronic heart failure.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    Neladenoson dalanate (BAY 10-67197) is a potent, selective, orally acitve partial adenosine A1 receptor (A1AR) agonist (EC50=0.1 nM) for the treatment of chronic heart failure.

    物理化学性质&存储条件

    分子量 752.73
    分子式 C35H35Cl2N7O4S2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    2-{4-[2-({[2-(4-chlorophenyl)-1,3-thiazol- 4-yl]methyl}sulfanyl)-3,5-dicyano-6-(pyrrolidin-1-yl)pyridin- 4-yl]phenoxy}ethyl L-alanyl-L-alaninate hydrochloride

    参考文献

    1. Meibom D, et al. ChemMedChem. 2017 May 22;12(10):728-737.

    2. Voors AA, et al. J Clin Pharmacol. 2017 Apr;57(4):440-451.

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