Nek2 inhibitor Compound 53

Chemical Structure : Nek2 inhibitor Compound 53

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货号: PC-27623Not For Human Use, Lab Use Only.

Nek2 inhibitor Compound 53 is a potent small molecule inhibitor of Nek2 with IC50 of 1.42 uM, >50-fold more potently than strong R-spine mutant Nek7SRS and Nek7WT.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

Nek2 inhibitor Compound 53 is a potent small molecule inhibitor of Nek2 with IC50 of 1.42 uM, >50-fold more potently than strong R-spine mutant Nek7SRS and Nek7WT.

物理化学性质&存储条件

分子量	487.62
分子式	C23H33N7O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-((6-(cyclohexylmethoxy)-9H-purin-2-yl)amino)-N-(3-(dimethylamino)propyl)benzenesulfonamide

参考文献

1. Byrne MJ, et al. Biochem J. 2020 Apr 30;477(8):1525-1539.

2. Sood A. Mol Neurobiol. 2026 Aug 4;63(1):808.