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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Lactate Dehydrogenase (LDH)-Nedosiran Sodium
Nedosiran Sodium

Chemical Structure : Nedosiran Sodium

CAS No.: 2247026-22-6

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Nedosiran Sodium (DCR-PHXC sodium)

货号: PC-23051Not For Human Use, Lab Use Only.

Nedosiran sodium is a GalNAc-dsRNA conjugated RNA interference agent designed to inhibit production of the hepatic lactate dehydrogenase (LDH) enzyme, the enzyme responsible for the common, final step of oxalate production in all three genetic subtypes of primary hyperoxaluria (PH).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Nedosiran sodium is a GalNAc-dsRNA conjugated RNA interference agent designed to inhibit production of the hepatic lactate dehydrogenase (LDH) enzyme, the enzyme responsible for the common, final step of oxalate production in all three genetic subtypes of primary hyperoxaluria (PH).

物理化学性质&存储条件

分子量 22183.60
分子式
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

参考文献

1. Hoppe B, et al. Kidney Int. 2022 Mar;101(3):626-634.

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