Naltrexone hydrochloride |CAS:16676-29-2 Probechem Biochemicals

Chemical Structure : Naltrexone hydrochloride

CAS No.: 16676-29-2

加入收藏

Naltrexone hydrochloride

货号: PC-45978Not For Human Use, Lab Use Only.

A potent, competitive antagonist for μ, κ, δ, and σ-opioid receptors with Ki of 0.0825 nM, 0.509 nM, and 8.02 nM, for MOR, KOR, and DOR, respectively.

规格	价格	库存	数量
250 mg	￥720	In stock
500 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

A potent, competitive antagonist for μ, κ, δ, and σ-opioid receptors with Ki of 0.0825 nM, 0.509 nM, and 8.02 nM, for MOR, KOR, and DOR, respectively; also inhibits IL-6 and TNFα production in human immune cell subsets following stimulation with ligands for intracellular TLRs; a TLR-4 antognist that inhibits LPS-induced TLR4 downstream NO production in microglia BV-2 cells (IC50=105 uM).

Alcoholism

Approved

物理化学性质&存储条件

分子量	377.8618
分子式	C20H24ClNO4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: ≥ 33 mg/mL
Chemical Name/SMILES	Morphinan-6-one, 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-, hydrochloride (1:1), (5α)-

参考文献

1. Codd EE, et al. J Pharmacol Exp Ther. 1995 Sep;274(3):1263-70.

2. Cant R, et al. Front Immunol. 2017 Jul 11;8:809.

3. Selfridge BR, et al. J Med Chem. 2015 Jun 25;58(12):5038-52.

Naltrexone hydrochloride

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Naltrexone hydrochloride

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.