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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Sodium Channel-NaV1.6 inhibitor Compound 103
NaV1.6 inhibitor Compound 103

Chemical Structure : NaV1.6 inhibitor Compound 103

CAS No.: 2154406-08-1

NaV1.6 inhibitor Compound 103

货号: PC-25010Not For Human Use, Lab Use Only.

NaV1.6 inhibitor Compound 103 is a potent, selective voltage-gated sodium channel NaV1.6 inhibitor with IC50 of 61 nM, >400-fold selective over NaV1.1 and NaV1.5.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

NaV1.6 inhibitor Compound 103 is a potent, selective voltage-gated sodium channel NaV1.6 inhibitor with IC50 of 61 nM, >400-fold selective over NaV1.1 and NaV1.5.

物理化学性质&存储条件

分子量 478.58
分子式 C22H24F2N4O2S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-4-((1-benzylpyrrolidin-3-yl)(methyl)amino)-2,6-difluoro-3-methyl-N-(thiazol-4-yl)benzenesulfonamide

参考文献

1. Patent WO2017201468 A1.

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