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首页-小分子抑制剂&激动剂-Others-Other Targets-NY0123
NY0123

Chemical Structure : NY0123

CAS No.: 1801911-70-5

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NY0123 (NY-0123)

货号: PC-63104Not For Human Use, Lab Use Only.

NY0123 is a novel potent Exchange proteins directly activated by cAMP (EPAC) antagonist with IC50 of 0.9 and 2.4 uM for EPAC1 and EPAC2, respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    NY0123 is a novel potent Exchange proteins directly activated by cAMP (EPAC) antagonist with IC50 of 0.9 and 2.4 uM for EPAC1 and EPAC2, respectively.
    NY0123 is more potent than ESI-09.
    NY0123 is a valuable pharmacological probes to facilitate our efforts in elucidating the biological functions of EPAC and developing potential novel therapeutics against human diseases.

    物理化学性质&存储条件

    分子量 399.656
    分子式 C16H13Cl3N4O2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    2-(5-tert-Butylisoxazol-3-yl)-2-oxo-N'-(3,4,5-trichlorophenyl)acetohydrazonoyl Cyanide

    参考文献

    1. Ye N, et al. J Med Chem. 2015 Aug 13;58(15):6033-47.

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