NU7441 (KU-57788) | DNA-PK inhibitor | Probechem Biochemicals

Chemical Structure : NU7441

CAS No.: 503468-95-9

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NU7441 (KU 57788, NU-7441, KU57788)

货号: PC-42782Not For Human Use, Lab Use Only.

NU7441 (KU-57788) is a highly potent and selective DNA-PK inhibitor (IC50=14 nM).

规格	价格	库存
10 mg	￥680	In stock
25 mg	￥1180	In stock
50 mg	￥1980	In stock
100 mg	￥3280	In stock
250 mg		Get quote

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生物&药学活性

NU7441 (KU-57788) is a highly potent and selective DNA-PK inhibitor (IC50=14 nM).
NU7441 (KU 57788) also modestly inhibits BRD4 and BRDT with IC50 of 1 uM and 3.5 uM respectively.
NU7441 (KU 57788) also stimulates Cas9-mediated genome editing.

物理化学性质&存储条件

分子量	413.4883
分子式	C25H19NO3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4H-1-Benzopyran-4-one, 8-(4-dibenzothienyl)-2-(4-morpholinyl)-

参考文献

1. Leahy JJ, et al. Bioorg Med Chem Lett. 2004 Dec 20;14(24):6083-7.

2. Robert F, et al. Genome Med. 2015 Aug 27;7:93.

3. Ember SW, et al. ACS Chem Biol. 2014 May 16;9(5):1160-71.

NU7441 (KU 57788, NU-7441, KU57788)

生物&药学活性

物理化学性质&存储条件

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NU7441 (KU 57788, NU-7441, KU57788)

生物&药学活性

物理化学性质&存储条件

参考文献

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