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首页-小分子抑制剂&激动剂-Apoptosis-MDM2-p53-NU-8165
NU-8165

Chemical Structure : NU-8165

CAS No.: 849723-20-2

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NU-8165 (NU8165;NU 8165)

货号: PC-60438Not For Human Use, Lab Use Only.

NU-8165 is a small molecule inhibitor of MDM2-p53 protein-protein interaction with IC50 of 16 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    NU-8165 is a small molecule inhibitor of MDM2-p53 protein-protein interaction with IC50 of 16 uM.

    物理化学性质&存储条件

    分子量 407.894
    分子式 C24H22ClNO3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    2-benzyl-3-(4-chlorophenyl)-3-(3-hydroxypropoxy)isoindolin-1-one

    参考文献

    1. Hardcastle IR, et al. J Med Chem. 2011 Mar 10;54(5):1233-43.

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