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首页-小分子抑制剂&激动剂-GPCR-Neurotensin Receptor-NTRC-808
NTRC-808

Chemical Structure : NTRC-808

CAS No.: 1643879-88-2

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NTRC-808 (NTRC808)

货号: PC-26997Not For Human Use, Lab Use Only.

NTRC-808 is a potent, selective nonpeptide partial agonist of GPCR neurotensin receptor type 2 (NTS2, NTSR2) with EC50 of 14 nM and Ki of 88 nM, is selective for NTS2 versus NTS1.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

NTRC-808 is a potent, selective nonpeptide partial agonist of GPCR neurotensin receptor type 2 (NTS2, NTSR2) with EC50 of 14 nM and Ki of 88 nM, is selective for NTS2 versus NTS1.

物理化学性质&存储条件

分子量 457.91
分子式 C23H24ClN3O5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-{[6-chloro-4-(2,6-dimethoxyphenyl)quinazolin-2-yl]carbonyl}-L-leucine

参考文献

1. James B Thomas, et al. Bioorg Med Chem Lett. 2015 Jan 15;25(2):292-6.

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