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首页-小分子抑制剂&激动剂-GPCR-Neurotensin Receptor-NTRC-739
NTRC-739

Chemical Structure : NTRC-739

CAS No.: 1612188-96-1

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NTRC-739 (NTRC739)

货号: PC-22265Not For Human Use, Lab Use Only.

NTRC-739 is a selective nonpeptide neurotensin receptor type 2 (NTS2/NTSR2) partial agonist with EC50 of 12 nM, binding Ki of 153 nM, displays no activity against NST1.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    NTRC-739 is a selective nonpeptide neurotensin receptor type 2 (NTS2/NTSR2) partial agonist with EC50 of 12 nM, binding Ki of 153 nM, displays no activity against NST1.

    物理化学性质&存储条件

    分子量 437.47
    分子式 C24H24FN3O4
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    1-({[1-(4-fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl]carbonyl}amino)cyclohexane carboxylic acid

    参考文献

    1. Thomas JB, et al. J Med Chem. 2014 Jun 26;57(12):5318-32.

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