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NTB-3119

Chemical Structure : NTB-3119

CAS No.: 2252473-48-4

NTB-3119 (NTB3119)

货号: PC-20080Not For Human Use, Lab Use Only.

NTB-3119 (NTB3119) is a novel benzothiopyranone derivative and anti-tuberculosis agent with potent in vitro activity against both drug-susceptible and drug-resistant tuberculosis clinical strains.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    NTB-3119 (NTB3119) is a novel benzothiopyranone derivative and anti-tuberculosis agent with potent in vitro activity against both drug-susceptible and drug-resistant tuberculosis clinical strains.
    NTB-3119 exhibited potent in vitro activity against both drug-susceptible and drug-resistant tuberculosis clinical strains.
    NTB-3119 displayed potent in vivo efficacy with bactericidal activity in an acute mouse model of tuberculosis.

    物理化学性质&存储条件

    分子量 455.50
    分子式 C21H24F3N3O3S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    2-(4-(cyclohexylmethyl)piperazin-1-yl)-8-nitro-6-(trifluoromethyl)-4H-thiochromen-4-one

    参考文献

    1. Xinbo Wang, et al. J Pharm Biomed Anal. 2023 Feb 5;224:115172.

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