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首页-小分子抑制剂&激动剂-Epigenetics-HDAC-NT160
NT160

Chemical Structure : NT160

CAS No.: 1418293-40-9

NT160 (NT-160)

货号: PC-21408Not For Human Use, Lab Use Only.

NT160 is a high affinity, selective class-IIa histone deacetylase (HDAC) inhibitor with IC50 of 80 nM (HDAC4), 600-fold selectivity over HDAC2 and 27-fold selectivity over HDAC8.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

NT160 is a high affinity, selective class-IIa histone deacetylase (HDAC) inhibitor with IC50 of 80 nM (HDAC4), 600-fold selectivity over HDAC2 and 27-fold selectivity over HDAC8.

物理化学性质&存储条件

分子量 418.42
分子式 C21H21F3N4O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-N-(1-(benzyl(methyl)amino)propan-2-yl)-4-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzamide

参考文献

1. Turkman N, et al. Eur J Med Chem. 2022 Jan 15;228:114011.

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