NSD2-PWWP1 inhibitor 34

Chemical Structure : NSD2-PWWP1 inhibitor 34

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货号: PC-22295Not For Human Use, Lab Use Only.

NSD2-PWWP1 inhibitor 34 is a potent, selective NSD2-PWWP1 binder / inhibitor with pIC50 of 8.2, pKd of 8.6.

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250 mg		Get quote

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生物&药学活性

NSD2-PWWP1 inhibitor 34 is a potent, selective NSD2-PWWP1 binder / inhibitor with pIC50 of 8.2, pKd of 8.6.
NSD2-PWWP1 inhibitor 34 shows pIC50 of 8.4 in NSD2 NanoBRET assay using U2OS cell lines.

物理化学性质&存储条件

分子量	417.51
分子式	C25H27N3O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	7-(5-Methyl-3-(2-methyl-5-(piperidin-1-ylmethyl)phenyl)isoxazol-4-yl)-2H-benzo[b][1,4]oxazin-3(4H)-one

参考文献

1. Carlino L, et al. J Med Chem. 2024 May 15. doi: 10.1021/acs.jmedchem.4c00215.