Chemical Structure : NSC95682
CAS No.: 20035-41-0
货号: PC-70078Not For Human Use, Lab Use Only.
NSC95682 is a potent and selective inhibitor of IRE1 endoribonuclease with IC50 of 0.41 uM.
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---|---|---|---|
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100 mg | ¥680 | In stock | |
250 mg | ¥1180 | In stock | |
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NSC95682 is a potent and selective inhibitor of IRE1 endoribonuclease with IC50 of 0.41 uM.
NSC95682 binds to IRE1 in a specific, reversible and dose-dependent manner and inhibits XBP-1 splicing induced pharmacologically in human cells.
NSC95682 inhibits XBP-1 splicing in vivo model of acute ER stress.
分子量 | 231.045 | |
分子式 | C8H7BrO3 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
3-Methoxy-6-bromosalicylaldehyde |
1. Volkmann K, et al. J Biol Chem. 2011 Apr 8;286(14):12743-55.
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