NSC95397 |CAS:93718-83-3 Probechem Biochemicals

Chemical Structure : NSC95397

CAS No.: 93718-83-3

加入收藏

NSC95397 (NSC-95397;NSC 95397)

货号: PC-60248Not For Human Use, Lab Use Only.

NSC95397 is a potent, selective, reversible Cdc25 dual specificity phosphatase inhibitor with Ki of 32/96/40 nM for Cdc25A/B/C, respectively.

规格	价格	库存
10 mg	￥1280	In stock
25 mg	￥1980	In stock
50 mg	￥3280	In stock
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

NSC95397 is a potent, selective, reversible Cdc25 dual specificity phosphatase inhibitor with Ki of 32/96/40 nM for Cdc25A/B/C, respectively.
NSC95397 displays 125- and 180-fold selectivity over VH1-related dual-specificity phosphatase and PTP1B.
NSC95397 shows significant growth inhibition in cancer cells and blocks G(2)/M phase transition.
NSC95397 also inhibits cellular MKP-1 and MKP-3 with IC50 of 13 uM.

物理化学性质&存储条件

分子量	310.38
分子式	C14H14O4S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2,3-bis[(2-Hydroxyethyl)thiol]-1,4-naphthoquinone

参考文献

1. Lazo JS, et al. Mol Pharmacol. 2002 Apr;61(4):720-8.

2. Nemoto K, et al. Prostate. 2004 Jan 1;58(1):95-102.

3. Vogt A, et al. Mol Cancer Ther. 2008 Feb;7(2):330-40.

4. Larsson DE, et al. Anticancer Res. 2010 Jan;30(1):149-56.

NSC95397 (NSC-95397;NSC 95397)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

NSC95397 (NSC-95397;NSC 95397)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.