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首页-小分子抑制剂&激动剂-Tyrosine Kinase-EGFR-NSC81111
NSC81111

Chemical Structure : NSC81111

CAS No.: 1678-14-4

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NSC81111 (NSC 81111)

货号: PC-38118Not For Human Use, Lab Use Only.

NSC81111 is a highly potent EGFR-TK inhibitor with IC50 of 0.15 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    NSC81111 is a highly potent EGFR-TK inhibitor with IC50 of 0.15 nM; NSC81111 displays stronger antiproliferative activities than erlotinib with IC50 values of <10 uM overexpressed EGFR-TK cancer cell lines: A431 and HeLa.

    物理化学性质&存储条件

    分子量 308.333
    分子式 C19H16O4
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    2,6-Bis(4-methoxyphenyl)-4H-pyran-4-one

    参考文献

    1. Jiwacharoenchai N, et al. Bioorg Med Chem Lett. 2022 Feb 15;58:128524.

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