NSC689857

Chemical Structure : NSC689857

CAS No.: 241127-79-7

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货号: PC-26625Not For Human Use, Lab Use Only.

NSC689857 is a potent EGFR and ubiquitin E3 ligase SCFSKP2 inhibitor with IC50 value of 36 uM for Skp2-Cks1 interaction, inhibit p27 ubiquitylation with IC50 of 30 uM.

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10 mg	￥2780	In stock
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NSC689857 is a potent EGFR and ubiquitin E3 ligase SCFSKP2 inhibitor with IC50 value of 36 uM for Skp2-Cks1 interaction, inhibit p27 ubiquitylation with IC50 of 30 uM.

物理化学性质&存储条件

分子量	407.51
分子式	C25H29NO4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	adamantan-1-ylmethyl 4-((2,5-dihydroxybenzyl)amino)benzoate

参考文献

1. Vuong W, et al. J Pharmacol Exp Ther. 2016 Nov;359(2):256-261.

2. Liu Q, et al. Behav Pharmacol. 2024 Jun 1;35(4):227-238.

3. Ungermannova D, et al. J Biomol Screen. 2013 Sep;18(8):910-20.

NSC689857

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物理化学性质&存储条件

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NSC689857

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物理化学性质&存储条件

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