NSC 311068 |CAS:66474-53-1 Probechem Biochemicals

Chemical Structure : NSC 311068

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NSC 311068 (NSC311068)

货号: PC-62521Not For Human Use, Lab Use Only.

NSC 311068 is a small molecule that directly tragets and inhibits STAT3/5, significantly and selectively suppresses the viability of AML cells with high level of TET1 expression both in vitro and in vivo.

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生物&药学活性

NSC 311068 is a small molecule that directly tragets and inhibits STAT3/5, significantly and selectively suppresses the viability of AML cells with high level of TET1 expression both in vitro and in vivo.
NSC 311068 shows no inhibitory effect on the viability of TET1-low AML (i.e., NB4) cells.

物理化学性质&存储条件

分子量	278.242
分子式	C10H6N4O4S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-((2,4-dinitrophenyl)thio)pyrimidine

参考文献

1. Jiang X, et al. Nat Commun. 2017 Dec 13;8(1):2099.

NSC 311068 (NSC311068)

生物&药学活性

物理化学性质&存储条件

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NSC 311068 (NSC311068)

生物&药学活性

物理化学性质&存储条件

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