欢迎访问ProbeChem中文网站，英文网站请访问www.probechem.com
    英文 |     中文

产品咨询: sales@probechem.com
订购: order@probechem.com

首页-小分子抑制剂&激动剂-Cytoskeleton/Cell Adhesion Molecules-Ezrin-NSC305787 hydrochloride
NSC305787 hydrochloride

Chemical Structure : NSC305787 hydrochloride

CAS No.: 53868-26-1

加入收藏

NSC305787 hydrochloride (NSC 305787 hydrochloride)

货号: PC-45561Not For Human Use, Lab Use Only.

NSC305787 hydrochloride is a small molecule inhibitor of Ezrin with Kd of 5.85 uM.

规格 价格 库存 数量
5 mg ￥2380 In stock
10 mg ￥3680 In stock
50 mg Get quote
100 mg Get quote
获取报价单
* 请选择数量再加入购物车
 or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

NSC305787 hydrochloride is a small molecule inhibitor of Ezrin with Kd of 5.85 uM.
NSC305787 inhibits ezrin phosphorylation, ezrin-actin interaction and ezrin-mediated motility of osteosarcoma (OS) cells in culture.
NSC305787 inhibits lung metastasis of ezrin-sensitive cells in mice; also inhibits SHIP-1 and SHIP-2.

物理化学性质&存储条件

分子量 481.8854
分子式 C25H31Cl3N2O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: 8 mg/mL
Chemical Name/SMILES

4-Quinolinemethanol, 6,8-dichloro-α-2-piperidinyl-2-tricyclo[3.3.1.13,7]dec-1-yl-, hydrochloride (1:1)

参考文献

1. Bulut G, et al. Oncogene. 2012 Jan 19;31(3):269-81.

2. Russo CM, et al. Bioorg Med Chem Lett. 2015 Nov 15;25(22):5344-8.

3. Çelik H, et al. J Biol Chem. 2016 Jun 17;291(25):13257-70.

备案号：沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

联系我们 sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

询单

  • *产品名称:
  • *姓名:
  • *邮箱:
  • *公司名称:
  • *询单数量:
  • *国籍:
  • 询单信息: