Chemical Structure : NSC305787
CAS No.: 785718-37-8
货号: PC-45560Not For Human Use, Lab Use Only.
NSC305787 is a small molecule inhibitor of Ezrin with Kd of 5.85 uM.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
5 mg | ¥2580 | In stock | |
10 mg | ¥3980 | In stock | |
25 mg | ¥5980 | In stock | |
50 mg | Get quote | ||
100 mg | Get quote |
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NSC305787 is a small molecule inhibitor of Ezrin with Kd of 5.85 uM.
NSC305787 inhibits ezrin phosphorylation, ezrin-actin interaction and ezrin-mediated motility of osteosarcoma (OS) cells in culture.
NSC305787 inhibits lung metastasis of ezrin-sensitive cells in mice; also inhibits SHIP-1 and SHIP-2.
分子量 | 445.4245 | |
分子式 | C25H30Cl2N2O | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
4-Quinolinemethanol, 6,8-dichloro-α-2-piperidinyl-2-tricyclo[3.3.1.13,7]dec-1-yl- |
1. Bulut G, et al. Oncogene. 2012 Jan 19;31(3):269-81.
2. Russo CM, et al. Bioorg Med Chem Lett. 2015 Nov 15;25(22):5344-8.
3. Çelik H, et al. J Biol Chem. 2016 Jun 17;291(25):13257-70.
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