Chemical Structure : NSC23925B
货号: PC-62666Not For Human Use, Lab Use Only.
NSC23925B is a small molecule agent that reverses MDR in cancer cells, reverses MDR in several drug-resistant cell lines expressing P-gp.
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NSC23925B is a small molecule agent that reverses MDR in cancer cells, reverses MDR in several drug-resistant cell lines expressing P-gp.
NSC23925B resensitizes cancer cell lines to paclitaxel, doxorubicin, mitoxantrone, etc.
NSC23925B significantly enhances in vivo antitumor activity of paclitaxel in MDR xenograft models, without increasing the level of paclitaxel toxicity.
分子量 | 421.362 | |
分子式 | C22H26Cl2N2O2 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
1. Duan Z, et al. J Med Chem. 2012 Apr 12;55(7):3113-21.
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