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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Filovirus-NSC157058
NSC157058

Chemical Structure : NSC157058

CAS No.: 1135191-02-4

NSC157058 (NSC 157058)

货号: PC-23171Not For Human Use, Lab Use Only.

NSC157058 is a potent, allosteric inhibitor of ZIKV NS2B-NS3 protease with IC50 of 0.82 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

NSC157058 is a potent, allosteric inhibitor of ZIKV NS2B-NS3 protease with IC50 of 0.82 uM.

物理化学性质&存储条件

分子量 189.99
分子式 C4HCl2N5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

5,6-dichloro-2H-[1,2,3]triazolo[4,5-b]pyrazine

参考文献

1. Shiryaev S.A., et al. Antivir. Res. 2017;143:218–229.

2. Lorenzo Cavina, et al. Molecules. 2024 Aug 27;29(17):4047.

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