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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-iGluR-NS3763
NS3763

Chemical Structure : NS3763

CAS No.: 70553-45-6

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NS3763 (NS 3763)

货号: PC-22610Not For Human Use, Lab Use Only.

NS3763 is a noncompetitive antagonist of GLUK5 receptor, inhibits domoate-induced increase in intracellular calcium mediated through the GLU(K5) of kainate receptors with IC50 of 1.6 uM, with no effect on GLU(K6) subtype.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

NS3763 is a noncompetitive antagonist of GLUK5 receptor, inhibits domoate-induced increase in intracellular calcium mediated through the GLU(K5) of kainate receptors with IC50 of 1.6 uM, with no effect on GLU(K6) subtype.

物理化学性质&存储条件

分子量 404.38
分子式 C22H16N2O6
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4,6-Bis(benzoylamino)-1,3-benzenedicarboxylic acid

参考文献

1. Christensen JK, et al. J Pharmacol Exp Ther. 2004 Jun;309(3):1003-10.

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