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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-GABA Receptor-NS16085
NS16085

Chemical Structure : NS16085

CAS No.: 1227253-85-1

NS16085 (NS 16085, NS-16085)

货号: PC-22281Not For Human Use, Lab Use Only.

NS16085 is a potent, selective alpha2/alpha3 subtype-selective GABA(A) receptor positive allosteric modulator, dsplays negligible efficacy at GABAA-α5 receptors.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

NS16085 is a potent, selective alpha2/alpha3 subtype-selective GABA(A) receptor positive allosteric modulator, dsplays negligible efficacy at GABAA-α5 receptors.

物理化学性质&存储条件

分子量 388.86
分子式 C22H17ClN4O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-chloro-3-{6-[5-(2-hydroxypropan-2-yl)-1H-1,3-benzodiazol-1-yl]pyridin-2-yl}benzonitrile

参考文献

1. de Lucas AG, et al. Biochem Pharmacol. 2015 Feb 1;93(3):370-9.

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