NS-638 |CAS:150493-34-8 Probechem Biochemicals

Chemical Structure : NS-638

CAS No.: 150493-34-8

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NS-638 (NS638, NS 638)

货号: PC-42385Not For Human Use, Lab Use Only.

NS-638 is a nonpeptide calcium channel blocker that dose dependently inhibits AMPA-stimulated [3H]GABA-release from cultured cortical neurons with IC50 of 4.3 uM.

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10 mg	￥1280	In stock
25 mg	￥2180	In stock
50 mg	￥3580	In stock
100 mg		Get quote

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生物&药学活性

NS-638 is a nonpeptide calcium channel blocker that dose dependently inhibits AMPA-stimulated [3H]GABA-release from cultured cortical neurons with IC50 of 4.3 uM.
NS-638 blocks K(+)-stimulated intracellular Ca(2+)-elevation in cultured cerebellar granule cells with IC50 of 3.4 uM.
NS-638 reversibly blocks N- and L-type Ca(2+)-channels in cultured chick dorsal root ganglion cells (1-30 uM).
NS-638 exhibits anti-ischemic properties in vivo.

物理化学性质&存储条件

分子量	325.7161496
分子式	C15H11ClF3N3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: ≥ 34 mg/mL
Chemical Name/SMILES	1H-Benzimidazol-2-amine, 1-[(4-chlorophenyl)methyl]-5-(trifluoromethyl)-

参考文献

1. Møller A, et al. Neurol Res. 1995 Oct;17(5):353-60.

2. Olesen SP, et al. Acta Neurol Scand. 1997 Apr;95(4):219-24.

NS-638 (NS638, NS 638)

生物&药学活性

物理化学性质&存储条件

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NS-638 (NS638, NS 638)

生物&药学活性

物理化学性质&存储条件

参考文献

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