(Rac)-Minzasolmin (NPT200-11) |CAS 1802518-63-3 Probechem Biochemicals

Chemical Structure : NPT200-11

CAS No.: 1802518-63-3

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NPT200-11 ((Rac)-Minzasolmin, (Rac)-UCB0599)

货号: PC-35764Not For Human Use, Lab Use Only.

NPT200-11 is an orally bioavailable and brain penetrating alpha-synuclein (ASYN) misfolding and aggregation inhibitor.

规格	价格	库存
5 mg	￥3880	In stock
10 mg	￥5580	In stock
25 mg	￥8980	In stock
100 mg		Get quote

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生物&药学活性

NPT200-11 ((Rac)-Minzasolmin, (Rac)-UCB0599) is an orally bioavailable and brain penetrating alpha-synuclein (ASYN) misfolding and aggregation inhibitor.
NPT200-11 reduced retinal alpha-synuclein pathology in cortex, reduced associated neuroinflammation (astrogliosis), normalized striatal levels of the dopamine transporter (DAT) and improved motor function in animal model of Parkinson's disease.

物理化学性质&存储条件

分子量	425.60
分子式	C23H31N5OS
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(1-(1H-indol-3-yl)hexan-2-yl)-2-(4-methylpiperazin-1-yl)thiazole-5-carboxamide

参考文献

1. Price DL, et al. Sci Rep. 2018 Nov 1;8(1):16165.

NPT200-11 ((Rac)-Minzasolmin, (Rac)-UCB0599)

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NPT200-11 ((Rac)-Minzasolmin, (Rac)-UCB0599)

生物&药学活性

物理化学性质&存储条件

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