NPD389 | ME2 inhibitor | Probechem Biochemicals

Chemical Structure : NPD389

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NPD389 (NPD 389)

货号: PC-49093Not For Human Use, Lab Use Only.

NPD389 is a potent, selective, fast-binding uncompetitive inhibitor of NADP+-dependent malic enzyme 2 (ME2) with IC50 of 4.63 uM, NPD389 is a mixed-type competitive inhibitor for the substrate L-malate and an uncompetitive inhibitor for the other substrate NAD+.

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生物&药学活性

NPD389 is a potent, selective, fast-binding uncompetitive inhibitor of NADP+-dependent malic enzyme 2 (ME2) with IC50 of 4.63 uM, NPD389 is a mixed-type competitive inhibitor for the substrate L-malate and an uncompetitive inhibitor for the other substrate NAD+.

物理化学性质&存储条件

分子量	352.342
分子式	C20H16O6
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3',6'-dihydroxy-4,4''-dimethoxy-[1,1':4',1''-terphenyl]-2',5'-dione

参考文献

1. Yi Wen, et al. Acta Pharmacol Sin. 2014 May;35(5):674-84.

NPD389 (NPD 389)

生物&药学活性

物理化学性质&存储条件

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NPD389 (NPD 389)

生物&药学活性

物理化学性质&存储条件

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