NPBA

Chemical Structure : NPBA

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货号: PC-21482Not For Human Use, Lab Use Only.

NPBA is a potent, selective pharmacological activator for K2P channel TASK-3 with EC50 of 6.7 uM (TASK-3 whole-cell currents), shows good selectivity between TASK channels.

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NPBA is a potent, selective pharmacological activator for K2P channel TASK-3 with EC50 of 6.7 uM (TASK-3 whole-cell currents), shows good selectivity between TASK channels.
NPBA shows no activity against other K2Ps at 10 uM, including TASK-1, TREK-1, TRESK, and THIK-1.
NPBA mitigated LPS-induced inflammation and lung injury by inhibiting TWIK2 channel.

物理化学性质&存储条件

分子量	353.30
分子式	C16H14F3N3O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(2-((4-nitro-2-(trifluoromethyl)phenyl)amino)ethyl)benzamide

参考文献

1. Fuyun Tian, et al. Mol Pharmacol. 2019 Jul;96(1):26-35.

NPBA

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物理化学性质&存储条件

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NPBA

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