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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Filovirus-NK-189
NK-189

Chemical Structure : NK-189

CAS No.: 2493976-08-0

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NK-189 (NK189)

货号: PC-23173Not For Human Use, Lab Use Only.

NK-189 is a potent, specific flaviviral serine protease NS2B-NS3 inhibitor with submicromolar activities in viral replication assays (EC50=0.89 μM, DENV-2).

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

NK-189 is a potent, specific flaviviral serine protease NS2B-NS3 inhibitor with submicromolar activities in viral replication assays (EC50=0.89 μM, DENV-2).

物理化学性质&存储条件

分子量 501.63
分子式 C29H35N5O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(S)-N-(1-(4-(benzyloxy)phenyl)-2-((4-guanidinobenzyl)amino)-2-oxoethyl)hexanamide

参考文献

1. Nikos Kühl, et al. J Med Chem. 2020 Aug 13;63(15):8179-8197.

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