NH4-13 | SIRT2 inhibitor | Probechem Biochemicals

Chemical Structure : NH4-13

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NH4-13 (SIRT2 inhibitor NH4-13)

货号: PC-72769Not For Human Use, Lab Use Only.

NH4-13 is a potent, SIRT2-selective inhibitor with IC50 of 87 nM, shows no inhibition against SIRT1/3/5/6 (IC50>50 uM).

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1 g		Get quote

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生物&药学活性

NH4-13 is a potent, SIRT2-selective inhibitor with IC50 of 87 nM, shows no inhibition against SIRT1/3/5/6 (IC50>50 uM).
NH4-13 (30 mg/kg) significantly impaired tumor growth in HCT-116 tumor xenograft.

物理化学性质&存储条件

分子量	719.808
分子式	C33H58IN3O4S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-((N2-((benzyloxy)carbonyl)-N6-tetradecanethioyl-L-lysyl)oxy)-N,N,N-trimethylethan-1-aminium iodide

参考文献

1. Jun Young Hong, et al. ACS Chem Biol. 2021 Jul 16;16(7):1266-1275.

NH4-13 (SIRT2 inhibitor NH4-13)

生物&药学活性

物理化学性质&存储条件

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NH4-13 (SIRT2 inhibitor NH4-13)

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物理化学性质&存储条件

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