NGP-555 | γ-secretase modulator | Probechem Biochemicals

Chemical Structure : NGP-555

CAS No.: 1304630-27-0

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货号: PC-22498Not For Human Use, Lab Use Only.

NGP-555 (NGP555) is a potent, selective γ-secretase modulator with Aβ42 IC50 of 10 nM.

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NGP-555 (NGP555) is a potent, selective γ-secretase modulator with Aβ42 IC50 of 10 nM.

分子量	406.52
分子式	C23H23FN4S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(5-Ethyl-2,4-dimethylphenyl)-4-[3-fluoro-4-(4-methyl-1H-imidazol-1-yl)phenyl]-2-thiazolamine

1. Pettersson M, et al. J Med Chem. 2024 Jun 7. doi: 10.1021/acs.jmedchem.4c00580.