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首页-小分子抑制剂&激动剂-Others-Other Targets-NGI-190
NGI-190

Chemical Structure : NGI-190

CAS No.: 2763063-58-5

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NGI-190

货号: PC-24838Not For Human Use, Lab Use Only.

NGI-190 is a potent, small molecule inhibitor of oligosaccharyltransferase (OST) with IC50 of 0.59 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

NGI-190 is a potent, small molecule inhibitor of oligosaccharyltransferase (OST) with IC50 of 0.59 uM.
NGI-190 demonstrates activity against both OST-A and OST-B, with preferential inhibition of OST-B.

物理化学性质&存储条件

分子量 486.55
分子式 C20H24F2N4O4S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-(3,3-difluoropyrrolidin-1-yl)-N-(5-ethylthiazol-2-yl)-5-(morpholinosulfonyl)benzamide

参考文献

1. Baro M, et al. Cell Chem Biol. 2025 Jun 19;32(6):839-853.e6.

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