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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Protein Phosphatase/PTP-NGD61181
NGD61181

Chemical Structure : NGD61181

CAS No.: 1266401-14-2

NGD61181 (NGD 61181)

货号: PC-21456Not For Human Use, Lab Use Only.

NGD61181 is a pyrazole-based SHIP2 inhibitor, has micromolar binding affinity and inhibitory activity, does not contain a phosphatase “warhead,” binds the active site of SHIP2.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

NGD61181 is a pyrazole-based SHIP2 inhibitor, has micromolar binding affinity and inhibitory activity, does not contain a phosphatase “warhead,” binds the active site of SHIP2.

物理化学性质&存储条件

分子量 518.60
分子式 C31H32F2N2O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-2-((3-(azepane-1-carbonyl)-2',4'-difluoro-[1,1'-biphenyl]-4-yl)oxy)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)acetamide

参考文献

1. Annis DA, et al. Comb Chem High Throughput Screen. 2009; 12(8): 760-771.

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