NE-2-6

Chemical Structure : NE-2-6

加入收藏

货号: PC-27889Not For Human Use, Lab Use Only.

NE-2-6 is a potent, selective thyroid peroxidase (TPO) inhibitor with IC50 of 13 nM, shows 496-fold selectivity for TPO over MPO and 68-fold selectivity for TPO over LPO.

规格	价格	库存	数量
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

NE-2-6 is a potent, selective thyroid peroxidase (TPO) inhibitor with IC50 of 13 nM, shows 496-fold selectivity for TPO over MPO and 68-fold selectivity for TPO over LPO.
NE-2-6 perturbs the heme-associated catalytic environment of TPO.
NE-2-6 directly represses TPO transcription in SNU-790 cells.
NE-2-6 (10 mg/kg) reduces serum T4 in Ad-TSHR289-immunized mice.

物理化学性质&存储条件

分子量	344.37
分子式	C20H16N4O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(benzo[d][1,3]dioxol-5-yl)-6-methyl-2-(pyridin-3-yl)imidazo[1,2-a]pyridin-3-amine

参考文献

1. Lee MG, et al. Antioxidants (Basel). 2026 Aug 4;15(8):967.

NE-2-6

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

NE-2-6

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.