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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Calcium Channel -NDC-1171
NDC-1171

Chemical Structure : NDC-1171

CAS No.: 892671-77-1

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NDC-1171 (NDC1171)

货号: PC-26650Not For Human Use, Lab Use Only.

NDC-1171 is a potent, selective positive allosteric modulator/ activator of sarcoplasmic/endoplasmic reticulum calcium ATPase (SERCA) pump, improves SERCA-mediated Ca2+ cycling, attenuates cardiac functional decline in mouse model of Duchenne muscular dystrophy (DMD).

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

NDC-1171 is a potent, selective positive allosteric modulator/ activator of sarcoplasmic/endoplasmic reticulum calcium ATPase (SERCA) pump, improves SERCA-mediated Ca2+ cycling, attenuates cardiac functional decline in mouse model of Duchenne muscular dystrophy (DMD).

物理化学性质&存储条件

分子量 310.78
分子式 C18H15ClN2O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3-chloro-4-methyl-N-(2-methylquinolin-8-yl)benzamide

参考文献

1. Narra N, et al. bioRxiv [Preprint]. 2026 Mar 9:2026.03.05.709950.

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