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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Matrix Metalloproteinase (MMP)-ND-336
ND-336

Chemical Structure : ND-336

CAS No.: 1807453-83-3

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ND-336 (ND336, ND 336)

货号: PC-70316Not For Human Use, Lab Use Only.

ND-336 (ND336) is a potent, selective inhibitor of the gelatinases MMP2 and MMP9 and MMP13 with Ki of 85, 150 and 120 nM, respectively.

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5 mg ￥2580 In stock
10 mg ￥3980 In stock
25 mg ￥5980 In stock
50 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

ND-336 (ND336) is a potent, selective inhibitor of the gelatinases MMP2 and MMP9 and MMP13 with Ki of 85, 150 and 120 nM, respectively.
ND-336 has minimal effect on other MMPs.
ND-336 accelerates diabetic wound healing by lowering inflammation and by enhancing angiogenesis and re-epithelialization of the wound, thereby reversing the pathological condition.

物理化学性质&存储条件

分子量 371.9
分子式 C16H17NO3S2 • HCl
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(4-(4-((thiiran-2-ylmethyl)sulfonyl)phenoxy)phenyl)methanamine

参考文献

1. Gao M, et al. Proc Natl Acad Sci U S A. 2015 Dec 8;112(49):15226-31.

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