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首页-小分子抑制剂&激动剂-Others-CaMK-NCS-382
NCS-382

Chemical Structure : NCS-382

CAS No.: 520505-01-5

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NCS-382 (NCS382)

货号: PC-49436Not For Human Use, Lab Use Only.

NCS-382 is a a gamma-hydroxybutyrate receptor (GHBR) antagonist, brain-penetrating high nanomolar-affinity ligand selective for the CaMKIIα hub domain, possesses antagonistic properties.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    NCS-382 is a a gamma-hydroxybutyrate receptor (GHBR) antagonist, brain-penetrating high nanomolar-affinity ligand selective for the CaMKIIα hub domain, possesses antagonistic properties.

    物理化学性质&存储条件

    分子量 218.252
    分子式 C13H14O3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (E)-2-(5-Hydroxy-5,7,8,9-tetrahydro-6H-benzo[7]annulen-6-ylidene)acetic acid

    参考文献

    1. Schmidt C, et al. Eur J Pharmacol. 1991 Oct 22;203(3):393-7.

    2. Maitre M, et al. J Pharmacol Exp Ther. 1990 Nov;255(2):657-63.

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