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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-iGluR-NBQX disodium
NBQX disodium

Chemical Structure : NBQX disodium

CAS No.: 479347-86-9

NBQX disodium

货号: PC-61720Not For Human Use, Lab Use Only.

NBQX disodium is the water soluble disodium salt of NBQX, which is a potent, selective and competitive AMPA receptor (AMPAR) antagonist with IC50 of 0.15 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

NBQX disodium is the water soluble disodium salt of NBQX, which is a potent, selective and competitive AMPA receptor (AMPAR) antagonist with IC50 of 0.15 uM.
NBQX disodium exhibits anticonvulsant activity in rodent seizure models.

物理化学性质&存储条件

分子量 380.24
分子式 C12H6N4O6SNa2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

100 mM in H2O

Chemical Name/SMILES

2,3-Dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulfonamide disodium salt

参考文献

1. Sheardown MJ, et al. Science. 1990 Feb 2;247(4942):571-4.

2. Klockgether T, et al. Ann Neurol. 1991 Nov;30(5):717-23.

3. Gill R, et al. Brain Res. 1992 May 15;580(1-2):35-43.

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