NBD-557 |CAS:333352-59-3 Probechem Biochemicals

Chemical Structure : NBD-557

CAS No.: 333352-59-3

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NBD-557 (NBD 557;NBD557)

货号: PC-45974Not For Human Use, Lab Use Only.

A potent HIV-1 entry inhibitor that blocks the gp120-CD4 interaction.

规格	价格	库存	数量
10 mg	￥3840	In stock
50 mg	￥8550	In stock

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生物&药学活性

A potent HIV-1 entry inhibitor that blocks the gp120-CD4 interaction; inhibits the fusion between HIV-1NL4-3-luc pseudotyped virus expressing HIV-1HXB2 (X4-tropic) envelope and U87-T4-CXCR4 cells with IC50 of 9.7 uM; inhibits the laboratory-adapted HIV-1 strains IIIB, MN, and V32 with IC50 of 5-16 uM.

HIV Infection

Preclinical

物理化学性质&存储条件

分子量	382.2953
分子式	C17H24BrN3O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Ethanediamide, N-(4-bromophenyl)-N'-(2,2,6,6-tetramethyl-4-piperidinyl)- (9CI)

参考文献

1. Zhao Q, et al. Virology. 2005 Sep 1;339(2):213-25.

2. Schön A, et al. Biochemistry. 2006 Sep 12;45(36):10973-80.

3. Curreli F, et al. Antimicrob Agents Chemother. 2014 Sep;58(9):5478-91.

NBD-557 (NBD 557;NBD557)

生物&药学活性

物理化学性质&存储条件

参考文献

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NBD-557 (NBD 557;NBD557)

生物&药学活性

物理化学性质&存储条件

参考文献

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