NAN-190 hydrobromide | 5-HT1A antagonist | Probechem Biochemicals

Chemical Structure : NAN-190 hydrobromide

CAS No.: 115338-32-4

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NAN-190 hydrobromide (NAN190 hydrobromide)

货号: PC-45732Not For Human Use, Lab Use Only.

NAN-190 hydrobromide is a potent, selective 5-HT1A receptor antagonist with Ki of 0.6 nM.

规格	价格	库存
50 mg	￥780	In stock
100 mg	￥1080	In stock
500 mg	￥2480	In stock
1 g		Get quote

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生物&药学活性

NAN-190 hydrobromide is a potent, selective 5-HT1A receptor antagonist with Ki of 0.6 nM.
NAN-190 also potently blocks the α2-adrenergic receptor.
NAN-190 antagonizes the stimulation by norepinephrine of phosphoinositide turnover in rat cortical slices.

物理化学性质&存储条件

分子量	474.3907
分子式	C23H28BrN3O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: 36.23 mg/mL
Chemical Name/SMILES	1H-Isoindole-1,3(2H)-dione, 2-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]-, hydrobromide (1:1)

参考文献

1. Claustre Y, et al. Eur J Pharmacol. 1991 Oct 29;204(1):71-7.

2. Zhang J, et al. J Neurosci. 2010 Feb 17;30(7):2433-41.

3. Glennon RA, et al. J Med Chem. 1988 Oct;31(10):1968-71.

NAN-190 hydrobromide (NAN190 hydrobromide)

生物&药学活性

物理化学性质&存储条件

参考文献

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NAN-190 hydrobromide (NAN190 hydrobromide)

生物&药学活性

物理化学性质&存储条件

参考文献

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