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首页-小分子抑制剂&激动剂-Epigenetics-Histone Methyltransferase (HMTase)-NAH-C3-GPKK
NAH-C3-GPKK

Chemical Structure : NAH-C3-GPKK

CAS No.:

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NAH-C3-GPKK

货号: PC-72717Not For Human Use, Lab Use Only.

NAH-C3-GPKK is a potent, selective protein N-terminal methyltransferase 1 (NTMT1) bisubstrate inhibitor with Kiapp of 7 nM in endogenous proteomes.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

NAH-C3-GPKK is a potent, selective protein N-terminal methyltransferase 1 (NTMT1) bisubstrate inhibitor with Kiapp of 7 nM in endogenous proteomes.
NAH-C3-GPKK also potently inhibit a methyltransferase complex HemK2-Trm112 (also known as KMT9-Trm112, IC50=0.3 uM).
NAH-C3-GPKK is the first potent inhibitor for HemK2/KMT9.

物理化学性质&存储条件

分子量 835.965
分子式 C36H61N13O10
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

参考文献

1. Dongxing Chen, et al. ACS Chem Biol. 2021 Jul 16;16(7):1234-1242.

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