N6022 |CAS:1208315-24-5 Probechem Biochemicals

Chemical Structure : N6022

CAS No.: 1208315-24-5

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N6022 (N 6022;N-6022)

货号: PC-44142Not For Human Use, Lab Use Only.

A potent and reversible S-Nitrosoglutathione reductase (GSNOR) inhibitor with IC50 of 20 nM.

规格	价格	库存
10 mg	￥1120	In stock
50 mg	￥3360	In stock
100 mg	￥5520	In stock

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生物&药学活性

A potent and reversible S-Nitrosoglutathione reductase (GSNOR) inhibitor with IC50 of 20 nM; reduces bronchoconstriction and pulmonary inflammation in a mouse model of asthma and demonstrates an acceptable safety profile.

Asthma

Phase 2 Clinical

物理化学性质&存储条件

分子量	414.4565
分子式	C24H22N4O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: ≥ 46 mg/mL
Chemical Name/SMILES	1H-Pyrrole-2-propanoic acid, 1-[4-(aminocarbonyl)-2-methylphenyl]-5-[4-(1H-imidazol-1-yl)phenyl]-

参考文献

1. Sun X, et al. ACS Med Chem Lett. 2011 Mar 11;2(5):402-6.

2. Sun X, et al. ACS Med Chem Lett. 2011 Mar 11;2(5):402-6.

3. Green LS, et al. Biochemistry. 2012 Mar 13;51(10):2157-68.

4. Blonder JP, et al. BMC Pulm Med. 2014 Jan 10;14:3.

N6022 (N 6022;N-6022)

生物&药学活性

物理化学性质&存储条件

参考文献

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N6022 (N 6022;N-6022)

生物&药学活性

物理化学性质&存储条件

参考文献

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