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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-Nucleoside Antimetabolite/Analog-N3PT
N3PT

Chemical Structure : N3PT

CAS No.: 13860-66-7

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N3PT (N3-pyridyl thiamine)

货号: PC-24830Not For Human Use, Lab Use Only.

N3PT (N3-pyridyl thiamine) is a potent and selective transketolase inhibitor, N3PT is pyrophosphorylated and then binds to transketolase with Kd of 22 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

N3PT (N3-pyridyl thiamine) is a potent and selective transketolase inhibitor, N3PT is pyrophosphorylated and then binds to transketolase with Kd of 22 nM.

物理化学性质&存储条件

分子量 336.28
分子式 C13H19Cl2N3OS
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3-((2-Amino-6-methylpyridin-3-yl)methyl)-5-(2-hydroxyethyl)-4-methylthiazol-3-ium chloride hydrochloride

参考文献

1. Thomas AA, et al. Bioorg Med Chem Lett. 2008 Mar 15;18(6):2206-10.

2. Thomas AA, et al. Bioorg Med Chem Lett. 2008 Jan 15;18(2):509-12.

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