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首页-小分子抑制剂&激动剂-Epigenetics-Histone Demethylase-N19-0881
N19-0881

Chemical Structure : N19-0881

CAS No.: 1613410-75-5

N19-0881 (KDM5-N19, N 19-0881)

货号: PC-22359Not For Human Use, Lab Use Only.

KDM5-N19 (N19-0881) is a potent, selective, αKG-competitive KDM5B inhibitor with IC50 of 2 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

KDM5-N19 (N19-0881) is a potent, selective, αKG-competitive KDM5B inhibitor with IC50 of 2 nM.

物理化学性质&存储条件

分子量 343.77
分子式 C17H14ClN3O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(5-((4-chloro-2-methylbenzyl)oxy)-1H-pyrazol-1-yl)isonicotinic acid

参考文献

1. Horton JR, et al. Cell Chem Biol. 2016 Jul 21;23(7):769-781.

2. Kai Tang, et al. J Med Chem. 2022 Oct 13;65(19):12979-13000.

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