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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-HIF/HIF Prolyl-hydroxylase-N-oxalylglycine
N-oxalylglycine

Chemical Structure : N-oxalylglycine

CAS No.: 5262-39-5

N-oxalylglycine (NOG, N-Oxaloglycine)

货号: PC-22621Not For Human Use, Lab Use Only.

N-oxalylglycine (NOG) is a broad-spectrum 2OG oxygenase inhibitor with IC50 of 0.36 uM, 12.3 uM, 11.1 uM and 0.15 uM for FIH, PHD2, aspartate/asparagine-β-hydroxylase (AspH) and JMJD5, respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

N-oxalylglycine (NOG) is a broad-spectrum 2OG oxygenase inhibitor with IC50 of 0.36 uM, 12.3 uM, 11.1 uM and 0.15 uM for FIH, PHD2, aspartate/asparagine-β-hydroxylase (AspH) and JMJD5, respectively.

物理化学性质&存储条件

分子量 147.09
分子式 C4H5NO5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-((Carboxymethyl)amino)-2-oxoacetic acid

参考文献

1. Thomas P Corner, et al. Chem Sci. 2023 Oct 27;14(43):12098-12120.

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