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首页-小分子抑制剂&激动剂-Others-Other Targets-N-methyl protoporphyrin IX
N-methyl protoporphyrin IX

Chemical Structure : N-methyl protoporphyrin IX

CAS No.: 79236-56-9

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N-methyl protoporphyrin IX (NMPP, N-Methylprotoporphyrin IX)

货号: PC-27606Not For Human Use, Lab Use Only.

N-methyl protoporphyrin IX (NMPP, N-MPP) is a selective Ferrochelatase (FECH) antagonist with Ki app pf 3 nM, inhibits heme synthesis, also inhibits nitric oxide synthase isoforms nNOS, iNOS, and eNOS with IC50 of 5-8 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

N-methyl protoporphyrin IX (NMPP, N-MPP) is a selective Ferrochelatase (FECH) antagonist with Ki app pf 3 nM, inhibits heme synthesis, also inhibits nitric oxide synthase isoforms nNOS, iNOS, and eNOS with IC50 of 5-8 uM.

物理化学性质&存储条件

分子量 576.70
分子式 C35H36N4O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3,3'-(3,8,13,17,23-pentamethyl-7,12-divinylporphyrin-2,18-diyl)dipropionic acid

参考文献

1. Smith CM, et al. Sci Rep. 2017 Feb 8;7:41975. doi: 10.1038/srep41975.

2. Beale SI, et al. Plant Physiol. 1982 Jun;69(6):1331-3.

3. Shi Z, et al. Biochem J. 2006;399(1):21-28.

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