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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-Androgen Receptor (AR)-N-desmethyl Enzalutamide
N-desmethyl Enzalutamide

Chemical Structure : N-desmethyl Enzalutamide

CAS No.: 1242137-16-1

N-desmethyl Enzalutamide (N-desmethyl MDV3100;N-desmethyl MDV 3100;N-desmethyl MDV-3100)

货号: PC-45933Not For Human Use, Lab Use Only.

Amajor metabolite of Enzalutamide (MDV3100) which is an androgen-receptor (AR) antagonist for treatment of prostate cancer..

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10 mg ¥1200 In stock
50 mg ¥5200 In stock
100 mg ¥9120 In stock

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Amajor metabolite of Enzalutamide (MDV3100) which is an androgen-receptor (AR) antagonist for treatment of prostate cancer.

物理化学性质&存储条件

分子量 450.4094
分子式 C20H14F4N4O2S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 48 mg/mL

Chemical Name/SMILES

Benzamide, 4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluoro-

参考文献

1. Tran C, et al. Science. 2009 May 8;324(5928):787-90.

2. Richards J, et al. Cancer Res. 2012 May 1;72(9):2176-82.

3. Gibbons JA, et al. Clin Pharmacokinet. 2015 Oct;54(10):1043-55.

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