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首页-小分子抑制剂&激动剂-Cytoskeleton/Cell Adhesion Molecules-Arp2/3 complex-N-WASP inhibitor 187-1
N-WASP inhibitor 187-1

Chemical Structure : N-WASP inhibitor 187-1

CAS No.: 380488-27-7

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N-WASP inhibitor 187-1 (Peptide 187-1)

货号: PC-23090Not For Human Use, Lab Use Only.

N-WASP inhibitor 187-1 is a 14-aa cyclic peptide that potently inhibits actin assembly induced by PIP2 (IC50=2 uM), binds and inhibits neural Wiskott-Aldrich syndrome protein (N-WASP) by an allosteric mechanism, inhibits N-WASP activation of the Arp2/3 complex.

规格 价格 库存 数量
1 mg ￥1880 In stock
5 mg ￥3980 In stock
10 mg ￥5980 In stock
25 mg Get quote
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

N-WASP inhibitor 187-1 is a 14-aa cyclic peptide that potently inhibits actin assembly induced by PIP2 (IC50=2 uM), binds and inhibits neural Wiskott-Aldrich syndrome protein (N-WASP) by an allosteric mechanism, inhibits N-WASP activation of the Arp2/3 complex.

物理化学性质&存储条件

分子量 1784.11
分子式 C96H122N18O16
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

cyclo(lLys-dPhe-dPro-dPhe-lPhe-dPro-lGln)2

参考文献

1. Peterson JR, et al. Proc Natl Acad Sci U S A. 2001 Sep 11;98(19):10624-9.

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