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首页-小分子抑制剂&激动剂-Others-Other Targets-N-Propargylglycine
N-Propargylglycine

Chemical Structure : N-Propargylglycine

CAS No.: 58160-95-5

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N-Propargylglycine (N-PPG)

货号: PC-27844Not For Human Use, Lab Use Only.

N-propargylglycine (N-PPG) is a covalent, irreversible suicide inhibitor of proline dehydrogenase (PRODH), activates mitochondrial PRODH decay, shows anticancer activity and brain-enhancing mitohormesis properties

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50 mg ￥580 In stock
100 mg ￥880 In stock
250 mg ￥1380 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

N-propargylglycine (N-PPG) is a covalent, irreversible suicide inhibitor of proline dehydrogenase (PRODH), activates mitochondrial PRODH decay, shows anticancer activity and brain-enhancing mitohormesis properties

物理化学性质&存储条件

分子量 113.12
分子式 C5H7NO2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-[(Prop-2-yn-1-yl)amino]acetic acid

参考文献

1. Scott GK, et al. Amino Acids. 2021 Dec;53(12):1927-1939.

2. Scott GK, et al. Mol Cancer Ther. 2019 Aug;18(8):1374-1385.

3. White TA, et al. Biochemistry. 2008 May 20;47(20):5573-80.

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